For years, Yale researchers David Breslow and Mustafa Khokha have worked together with a similar challenge in their ...

近日，马德里自治大学等机构的科学家在 《Journal of Extracellular Vesicles》 发表的研究，成功破解了这一谜题。他们通过全基因组 CRISPR/Cas9 筛选，锁定了名为 COMMANDER 复合体的蛋白质机器，它正是调控细胞外囊泡摄取的关键 “守门人”。这款此前以细胞膜回收功能闻名的蛋白质复合体，实则是 “全能派送协调员”——不仅主导囊泡进入细胞的 “早期签收” ...

2025年9月24日, Nature发文《In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma》，这篇文章是哈佛医学院的Marcela V. Maus教授，她也是麻省总医院细胞免疫治疗项目的主任。

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Künzel, Associate Director in the Functional Genomics department at AstraZeneca, about the application of arrayed ...

RNAi (RNA interference) and CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) screening are two powerful techniques at the forefront of functional genomics research. Both techniques ...

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide. This prevalent condition is also linked to other metabolic disorders, including type 2 ...

Horizon Discovery Group plc (LSE: HZD) (“Horizon” or “the Company”), a global leader in gene editing and gene modulation technologies, today announced the extension of its CRISPR Screening Service to ...

Tulane University researchers have developed an enhanced CRISPR-based tuberculosis test that works with a simple tongue swab, a potential breakthrough that could allow easier, community-based ...

An artistic rendering of CRISPR-enhanced T-cells attacking a tumor. Research has shown that the gene-editing system CRISPR can modulate T cell behavior to make them better cancer killers without ...

Drug developers are consistently aiming to enhance clinical relevance in drug discovery. CRISPR has emerged as a versatile tool to accelerate the entire drug discovery process, with arrayed CRISPR ...