研究团队采用名为MCC ultra的新技术,将人类基因组图谱绘制精度提升至单个碱基对水平,从而揭示了基因是如何被调控的,即身体如何在正确的细胞、正确的时间决定开启或关闭哪些基因。这一突破为科学家理解遗传差异如何导致疾病提供了强大的新方法,并为药物发现开辟了新途径。
In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...
Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing ...
A live C. elegans animal with the mitochondria in its nervous system decorated with red and green fluorescent proteins. “Mitochondrial DNA is essential for cell function,” Dr Hahn said. “But as we age ...
In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises ...
Scientists at Children's Medical Research Institute (CMRI) have made a major discovery about cancer cells. This new ...
In two experiments, researchers have found that introducing people to "mental models" about how mRNA vaccination works and ...
The findings may have important implications for diseases linked to mitochondrial dysfunction. A newly identified form of DNA damage inside mitochondria, the small structures that supply energy to our ...