Deinococcus radiodurans is renowned for its extraordinary resistance to ionising radiation and other environmental stresses. This bacterium employs a combination of passive and active mechanisms to ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Poly(ADP‐ribose) polymerases (PARPs) are a family of enzymes that play a crucial role in maintaining genomic integrity by detecting DNA damage and facilitating its repair. By catalysing the covalent ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

Results from a VHIO-led study show that MYC targeting by Omomyc induces tumor DNA damage in patient-derived preclinical ...

Circular DNA, thought to be an accidental byproduct, is borrowing the cell’s DNA repair mechanisms to copy itself DURHAM, N.C. -- Like its viral cousins, a somewhat parasitic DNA sequence called a ...

A novel technology combined with optical tweezer C-trap technology gives researchers new insight into DNA repair mechanisms. Researchers at the University of Pittsburgh (PA, USA) have developed a ...

Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging. Researchers at ...

Cedars-Sinai researchers have created TY1, an experimental RNA-based drug that helps the body repair damaged DNA and restore injured tissue. The idea came from studying tiny molecular “messages” ...

(Nanowerk News) A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA. Such mistakes are frequent in code-copying process in ...

"Use it or lose it" goes the adage, applied liberally to everything from our muscles to our minds, especially as we age. Yet when it comes to the brain, such usage is not entirely a good thing: While ...

Scientists used magnetic tweezers to reveal how the RNA molecule ‘NIHCOLE’ repairs cell damage, hindering cancer treatments such as radiotherapy. If you want to defeat an enemy, one strategy you can ...